Antibiotic a-7413 mixture comprising factors a,b,c and d and...

Details Antibiotic a-7413 mixture comprising factors a,b,c and d and... Antibiotic a-7413 mixture comprising factors a,b,c and d and...

C - Chemistry, Metallurgy

12

P

195/96

C12P 1/06 (2006.01) A23K 1/17 (2006.01) A61K 35/74 (2006.01) C07G 11/00 (2006.01) C07K 4/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1090728

Abstract The present invention relates to an antibiotic A-7413 mixture comprising factors A, B, C and D, and A-7413 factor A, A-7413 factor B, A-7413 factor C and A-7413 factor D, its production by cultivation of Antinoplanes sp. NRRL 8122 or a A-7413 producing mutant thereof, its separation from the culture media; and optionally the isolation of factors A, B, C and D. It also relates to the C1-C4- alkyl esters, C1-C5-acyl esters and thiol-C-2-C4-carboxylic acid derivatives of A-7413 factors A, B and C; and the physiologically acceptable salts of factors A, B and C and their C1-C5-acyl esters and thiol-C2-C4-carboxylic acid derivatives.

269468

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