Antibiotic agents

A - Human Necessities – 61 – P

Patent

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Details

A61P 31/00 (2006.01) A61K 31/7048 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2375358

Methods of treating a microbial infection comprising administering to a patient in need of such treatment are disclosed. In one aspect the method comprises administering to a patient in need of such treatment a therapeutically effective amount of Erythromycin B (or a pharmaceutically acceptable derivative thereof). In another aspect the method comprises a pharmaceutical composition comprising at least 50 % by weight of Erythromycin B (or a pharmaceutically acceptable derivative thereof) of the total weight of antibiotic present in the composition. Also disclosed are 2'-esters of Erythromycin B and Erythromycin B enol ether.

L'invention concerne des techniques permettant de traiter un patient atteint d'une infection microbienne nécessitant un tel traitement. Dans un mode de réalisation, cette technique consiste à administrer à un patient qui le nécessite une quantité thérapeutique efficace d'érythromycine B (ou un dérivé pharmaceutiquement acceptable). Dans un autre mode de réalisation, la technique consiste en une composition pharmaceutique comprenant au moins 50 % en poids d'érythromycine B (ou d'un dérivé pharmaceutiquement acceptable) du poids total d'antibiotique présent dans cette composition. L'invention concerne également 2'-esters d'érythromycine B et d'érythromycine B enol éther.

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