Antibiotic and processes for its manufacture

Details Antibiotic and processes for its manufacture Antibiotic and processes for its manufacture

C - Chemistry, Metallurgy

12

P

195/95, 260/275.

C12P 19/44 (2006.01) C07D 491/14 (2006.01) C07D 491/16 (2006.01) C12P 17/18 (2006.01)

Patent

CA 1079213

Abstract of the Disclosure The invention relates to the new antibiotic Lysolipin, including two components X and I, and derivatives thereof. Lysolipin is formed when the strain Streptomyces violaceoniger (Waksman et Curtis) Waksman et Henrici T? 96, which strain has been deposited under the reference NRRL 8097 at the Northern Regional Laboratory, U.S. Department of Agriculture, Peoria, Illinois, is cultured in a nutrient medium. The structure of Lysolipin I has been elucidated; it has the formula Image Lysolipin and its derivatives have antibacterial action and an action against yeast - like fungi, such as Candida albicans. Its antibiotic action probably depends on an inhibition of the cell wall synthesis.

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