Antibiotic c-7 catechol-substituted cephalosporin compounds,...

Details Antibiotic c-7 catechol-substituted cephalosporin compounds,... Antibiotic c-7 catechol-substituted cephalosporin compounds,...

C - Chemistry, Metallurgy

07

D

C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01)

Patent

CA 2048832

CT-2020 -1- Abstract The present invention relates to new cephalosporins of the formula Image I wherein R1 and R2 are hydrogen or carboxy, with the proviso that both cannot be the same; R3 is hydrogen or acetyl; and R4 is a radical selected from the group consisting of Image or Image in which n is 1 or 2, R5 is hydrogen or acetyl, and R6 is hydrogen, a lower C1-3 alkyl, or a radical selected from the group consisting of Image or Image in which n and R5 are as defined above. CT-2020 -2- In another aspect, this invention relates to processes for the preparation of the compounds of Formula I, to pharmaceutical compositions containing at least one compound of Formula I, and to intermediates in their preparation.

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