Antibiotic compositions

Details Antibiotic compositions Antibiotic compositions

A - Human Necessities

61

K

167/187

A61K 31/545 (2006.01)

Patent

CA 1132905

ABSTRACT A vacuum sealed vial, which contains a solid antibiotic composition comprising 7.beta.-[2-(2-imino-4-thiazolin -4-yl)acetamido]-3-{1-[2-(N,N-dimethylam- ino)ethyl]-1H-tetrazol-5-yl}thiomethyl-3-cephem-4-carboxylic acid dihydrochloride or its hydrate and a pharmaceutically acceptable carbonic acid salt, the ratio of the hydrogen chloride moiety of 7.beta.[2-(2-imino-4-thiazoline-4-yl)acetamido]-3- {1-[2-(N,N-dimethylamino)ethyl]-1H-tetrazol-5-yl}thiomethyl-3-cephem-4-carboxylic acid dihydrochloride or its hydrate relative to the pharmaceutically acceptable carbonic acid salt being substantially 1:1 to 2 equivalents, the pressure in the vial being in the range of from 0 to 300 mm Hg.

385979

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