Antibiotic compounds and their preparation

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) A01N 43/90 (2006.01) A61K 31/365 (2006.01) C07D 493/22 (2006.01) C07H 19/01 (2006.01) C12P 17/08 (2006.01) C12P 17/18 (2006.01)

Patent

CA 1313155

ABSTRACT Antibiotic compounds and their preparation Compounds as described having the partial formula Image These compounds may have a 5-OH or -OMe group and at the 25- position an isopropylene group substituted by methyl, ethyl or isopropyl. The compounds may be used in agriculture or medicine as antiparasitics, and may be prepared by culturing certain Streptomyces strains, in particular Streptomyces thermoarchaensis NCIB 12015.

490631

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