Antibiotic conjugates

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/00 (2006.01) A61K 47/48 (2006.01) A61P 31/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2476448

This invention features a compound of the following formula (I): wherein T is a transportophore, L is a bond or linker, and C is an antibiotic therapeutic agent, the transportophore is covalently bonded to the antibiotic therapeutic agent via the bond or the linker, and the transportophore is an azithromycin derivative or crown ether derivative.

La présente invention concerne un composé de la formule (1) suivante : dans laquelle T est un transportophore, L est une liaison ou un segment de liaison, et C est un agent thérapeutique antibiotique, le transportophore étant lié par covalence à l'agent thérapeutique antibiotique via la liaison ou le segment de liaison, et le transportophore étant un dérivé d'azithromycine ou un dérivé d'éther couronne.

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