Antibiotic cryptdin peptides and methods of their use

Details Antibiotic cryptdin peptides and methods of their use Antibiotic cryptdin peptides and methods of their use

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2204995

The present invention provides substantially purified cryptdin peptides and nucleic acid molecules encoding cryptdin peptides. The invention further provides methods for detecting inflammatory pathologies in a subject and methods for treating an inflammatory pathology in a subject by administering a pharmaceutical composition containing a cryptdin peptide. Representative cryptdin peptides are presented in the figure.

La présente invention concerne des peptides sensiblement purifiés du type cryptdines et des molécules d'acides nucléiques codant pour ces peptides de type cryptidine. L'invention concerne en outre des procédés pour détecter des pathologies inflammatoires chez un sujet et des procédés pour traiter une pathologie inflammatoire chez un sujet en administrant une composition pharmaceutique contenant un peptide du type cryptdine. Des peptides de type cryptdine qui sont représentatifs sont présentés sur la figure.

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