Antibiotic crystalline epimer

Details Antibiotic crystalline epimer Antibiotic crystalline epimer

C - Chemistry, Metallurgy

07

D

260/244.2

C07D 498/04 (2006.01) C07D 505/00 (2006.01)

Patent

CA 1138867

-1- Abstract The diammonium salt of the oxa-.beta.-lactam anti- biotic of the formula Image I wherein the chiral center of the .alpha.-carboxy-p-hydroxy- phenylacetyl side chain has the D-configuration in crystalline form substantially free of the L-diammonium salt. This invention also relates to a process for preparing the crystalline D-diammonium salt of the above formula.

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