Antibiotic derivatives

Details Antibiotic derivatives Antibiotic derivatives

C - Chemistry, Metallurgy

07

H

260/230.5

C07H 15/22 (2006.01) C07C 271/22 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1046513

ABSTRACT OF THE DISCLOSURE Derivatives of kanamycin A and B have been prepared which possess substantially improved antibacterial activity. Two examples of such agents are 1-[L-(-)-.delta.-amino-.alpha.-hydroxyvaleryl]- kanamycin A [IVa, BB-K23] and 1-[L-(-)-.beta.-amino-.alpha.-hydroxypropionyl]- kanamycin B [IVa, BB-K122].

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