Antibiotic derivatives, derived from cephalosporins

C - Chemistry – Metallurgy – 07 – D

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C07D 501/34 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/20 (2006.01) C07D 501/24 (2006.01) C07D 501/46 (2006.01) C07D 501/56 (2006.01)

Patent

CA 1191838

-20- entitled: New antibiotic derivatives, derived from cephalo- sporins ABSTRACT OF THE DISCLOSURE The present invention relates to derivatives of the family of cephalosporins, of formula: Image in which - C=O-OA is an acid, a salt or an ester of this acid, Rl is a group of form Image in which RA-and RB are H or alkyl or form a saturated cyclobutyl or cyclopentyl cycle and RC is H or COOH, R2 is a COOCH2-RD group in which RD is 1, 3-thiazol-4-yl or thiazolium. The invention also relates to a process for preparing the pro- ducts of formula (I) and to drugs Containing said products.

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