Antibiotic formulations, unit doses, kits, and methods

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/7036 (2006.01)

Patent

CA 2622193

An aqueous or powder composition includes anti-gram-negative antibiotic or salt thereof being present at an amount ranging from about 100 mg/ml to about 200 mg/ml. Another aqueous or powder composition includes anti-gram-positive antibiotic or salt thereof being present at a concentration ranging from about 0.6 to about 0.9 of the water solubility limit, at 25~C and 1.0 atmosphere, of the anti-gram-positive antibiotic or salt thereof. Other embodiments include unit doses, kits, and methods.

La présente invention concerne une composition aqueuse ou pulvérulente à base d'antibiotique anti-Gram-négatif ou de l'un de ses sels, dosée à 100 à 200 mg/ml. L'invention concerne également une autre composition analogue mais dosée à une concentration correspondant à environ 0,6 à 0,9 de la limite de solubilité dans l'eau à 25 °C sous une atmosphère de 1. D'autres modes de réalisation portent sur les doses posologiques, nécessaires, et procédés.

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