Antibiotic kit and composition and uses thereof

Details Antibiotic kit and composition and uses thereof Antibiotic kit and composition and uses thereof

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 9/107 (2006.01) A61K 31/194 (2006.01) A61K 31/4164 (2006.01) A61K 47/10 (2006.01) A61P 17/00 (2006.01) A61P 17/02 (2006.01) A61P 29/00 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2611577

The present invention relates to a therapeutic kit to provide a safe and effective dosage of an antibiotic agent, including an aerosol packaging assembly including: a container accommodating a pressurized product; and an outlet capable of releasing the pressurized product as a foam, wherein the pressurized product comprises a foamable composition including: an antibiotic agent; at least one organic carrier selected from the group consisting of a hydrophobic organic carrier, an organic polar solvent, an emollient and mixtures thereof, at a concentration of about 2 % to about 50 % by weight, a surface- active agent, about 0.01 % to about 5 % by weight of at least one polymeric additive selected from the group consisting of a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent, water; and liquefied or compressed gas propellant at a concentration of about 3 % to about 25 % by weight of the total composition.

La présente invention concerne un kit thérapeutique destiné à délivrer une dose sans danger et efficace d'un agent antibiotique, y compris un conditionnement pour aérosol. Ledit kit inclut un récipient contenant un produit sous pression et un orifice de sortie capable de libérer le produit sous pression sous la forme d'une mousse. Ledit produit sous pression comprend une composition moussante qui inclut : un agent antibiotique; au moins un support organique choisi dans le groupe comprenant un support organique hydrophobe, un solvant polaire organique, un émollient et leurs mélanges, à une concentration comprise entre environ 2 % et environ 50 % en poids, un agent tensioactif, d'environ 0.01 % à environ 5 % en poids d'au moins un additif polymère choisi dans le groupe comprenant un agent bioadhésif, un agent gélifiant, un agent filmogène et un agent de changement de phase, de l'eau; et un gaz propulseur liquéfié ou compressé à une concentration comprise entre environ 3 % et environ 25 % en poids de la composition totale.

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