C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) C12N 9/00 (2006.01) C12N 15/52 (2006.01) C12N 15/63 (2006.01) C12P 7/62 (2006.01) C12P 17/06 (2006.01) C12P 17/10 (2006.01)
Patent
CA 2322105
The nucleic acid and amino acid sequences of .alpha.1, .alpha.2, .beta. and .epsilon. subunits of acetyl-CoA carboxylase (ACCase) from Streptomyces coelicolor are provided. This subunit structure differs from that of known acyl carboxylases. Materials and methods are provided of increasing ACCase activity and production of secondary metabolites (such as polyketides and especially antibiotics) by causing expression in Streptomyces of such nucleic acid. Also provided are methods of increasing ACCase activity and production of secondary metabolites (such as polyketides and especially antibiotics) by culturing Streptomyces in the presence of exogenous malonate.
Gramajo Hugo Cesar
Rodriguez Eduardo Jose
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Plant Bioscience Limited
LandOfFree
Antibiotic production (ii) does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibiotic production (ii), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibiotic production (ii) will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1519192