Antibiotic protein and method of production

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/31 (2006.01) A01N 63/02 (2006.01) A61K 39/07 (2006.01) C07K 14/32 (2006.01) C07K 19/00 (2006.01) C12N 9/56 (2006.01) C12N 15/57 (2006.01) C12N 15/62 (2006.01) C12N 15/75 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2334043

The invention provides an antibiotic protein having the properties of a native Bacillus subtilis TasA protein. The invention also provides a method of translocating a desired protein across a membrane by expressing the desired protein as a fusion with a SipW recognition sequence in a membrane-bound genetic expression system. When a sporulating bacterium is employed as the membrane-bound expression system, the domain consisting of the desired protein is cleaved from the fusion protein and secreted into the resultant spores.

L'invention concerne une protéine antibiotique possédant les propriétés d'une protéine native TasA de Bacillus subtilis. L'invention concerne également un procédé permettant de réaliser la translocation d'une protéine désirée à travers une membrane, par expression de ladite protéine sous forme de fusion avec une séquence de reconnaissance SipW, dans un système d'expression génétique lié à la membrane. Lorsqu'on utilise une bactérie sporulée comme système d'expression génétique lié à la membrane, le domaine comprenant la protéine désirée est coupé de la protéine de fusion et sécrété dans les spores résultantes.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Antibiotic protein and method of production does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibiotic protein and method of production, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibiotic protein and method of production will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1764206

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.