Antibiotic(s)-polymer combination

Details Antibiotic(s)-polymer combination Antibiotic(s)-polymer combination

A - Human Necessities

61

K

A61K 45/08 (2006.01) A61K 9/00 (2006.01) A61K 31/7036 (2006.01) A61K 47/10 (2006.01) A61K 47/32 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2378487

The present invention relates to an antibiotic(s)-polymer combination, which under physiological conditions guarantees the continuous release of antibiotics over a period of several days and can be used in human and veterinary medicine. The invented antibiotic(s)--polymer combination is characterized by the fact that in a homogeneous polymer mixture, consisting of one or more hydrophobic polymers from the groups of poly(methacrylic acid esters), the poly(acrylic acid esters) and the poly(methacrylic acid ester-co- acrylic acid esters) and one or more hydrophilic polymers from the group of polyethers, one or more slightly water--soluble antibiotics from the groups of aminoglycoside antibiotics, the lincosamide antibiotics, the tetracycline antibiotics and quinolone antibiotics, possibly an easily water- soluble antibiotic from the groups of aminoglycoside antibiotics, the lincosamide antibiotics and the tetracycline antibiotics, and possibly one or more organic adjuvants are suspended, and that this suspension forms a composite.

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