C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
195/89, 195/95
C12P 19/44 (2006.01) A61K 35/00 (2006.01) A61K 35/66 (2006.01) A61K 35/74 (2006.01) A61K 39/00 (2006.01) C07C 11/00 (2006.01) C07G 11/00 (2006.01) C12P 1/00 (2006.01) C12P 1/04 (2006.01) C12P 1/06 (2006.01) C12P 13/00 (2006.01)
Patent
CA 1072470
Abstract of the Disclosure This invention relates to a family of new antibiotic substances which can be used alone or in combination with one another. These substances are teichomycin A1 and A2 and are prepared by cultivating the strain Actimoplanes teichomyceticus nov. sp. ATCC 31121 or an equivalent thereof in an aqueous nutrient medium containing an assimilable source carbon and nitrogen, and inorganic salts until a substantial antibiotic activity is present in the medium and recovery the new antibiotic substances from the medium. The process used can also produce these new antibiotics together with other metabolites named respectively teichomycin A3, antibiotic factor 8327 factor B and antibiotic 8327 factor C. The new antibiotic of this invention are particularly useful as they are active against bacteria resistant to widely used antibiotics such as penicillin, tetracycline, streptomycin, bacitracin, cephalosporin rifamycin, neomycin and chloram- phemical. Hence they are useful in controlling infectious diseases in animals, as growth promoting agents are for disinfection of areas and instruments.
247140
Bardone Maria R.
Beretta Grazia
Coronelli Carolina
Parenti Francesco
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