Antibiotics

Details Antibiotics Antibiotics

A - Human Necessities

61

K

167/187

A61K 31/545 (2006.01) A61K 31/43 (2006.01)

Patent

CA 1055395

ABSTRACT OF THE DISCLOSURE A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which we designate clavulanic acid has the formula (I): Image (I) In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of ?-lactum antibiotics against many ?-lactamase producing bacteria.

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