Antibiotics r106

Details Antibiotics r106 Antibiotics r106

C - Chemistry, Metallurgy

12

P

195/89, 530/7.06

C12P 21/02 (2006.01) A61K 38/00 (2006.01) C07K 7/06 (2006.01) C12N 1/14 (2006.01)

Patent

CA 1334180

Novel antibiotics R106 represented by general formula (I): Image ... (I) wherein: R is methyl or ethyl; X1 is MePhe, .beta.-HOMePhe or Phe; X2 is allo-Ile, Val or Leu; X3 is MeVal or Val; X4 is .beta.-HOMeVal, .gamma.-HOMeVal, MeVal, Val, N,.beta.-MeAsp, .beta.-HOMePhe, MePhe, MeDH2,3Val or MeDH3,4Val are useful as therapeutic agents for fungal infection.

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