Antibodies

Details Antibodies Antibodies

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2163345

The invention provides antibodies with altered ability to fix complement. The invention further relates to pharmaceutical, therapeutic and diagnostic compositions containing said antibodies and to methods of therapy and diagnosis using said antibodies. The invention additionally provides a method of modulating the function of cell surface associated antigens using said antibodies. Also provided are processes for preparing said antibodies.

L'invention concerne des anticorps présentant une capacité modifiée de fixation à un complément. L'invention concerne, de plus, des compositions pharmaceutiques, thérapeutiques et diagnostiques contenant lesdits anticorps, ainsi que des procédés thérapeutiques et diagnostiques utilisant lesdits anticorps. Elle concerne, de plus, un procédé de modulation de la fonction d'antigènes associés à la surface d'une cellule au moyen desdits anticorps. Elle concerne également des procédés de préparation desdits anticorps.

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