Antibodies against antigen presenting cells and uses thereof

Details Antibodies against antigen presenting cells and uses thereof Antibodies against antigen presenting cells and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 16/46 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61P 31/06 (2006.01) A61P 31/12 (2006.01) A61P 33/12 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2591138

Antibodies to antigen presenting cells may be utilized to interfere with the interaction of the antigen presenting cell and immune cells, including T cells, Peptides may be linked to said antibodies thereby generating an immune response to such peptides. Preferably peptides linked to the antibodies are associated with autoimmunity.

Selon l'invention, des anticorps de cellules présentatrices d'antigène peuvent être utilisés pour agir sur l'interaction entre la cellule présentatrice d'antigène et des cellules immunitaires, notamment des lymphocytes T. Des peptides peuvent être liés auxdits anticorps, ce qui produit une réaction immunitaire à ces peptides. Les peptides liés aux anticorps sont de préférence associés à l'auto-immunité.

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