C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2573313
The invention relates to a method of producing antibodies that bind to cancer cells but not to human blood cells or tissue cells. The method comprises collecting antiserum from non-human subjects immunized with non-human cancerous cells, contacting the antiserum with cancer cells to provide masked cancer cells, immunizing a subject with the masked cancer cells and recovering the antibodies that bind to the cancer cells. Another method of providing the masked cancer cells is to contact the cancer cells with one or more antibodies to receptors present on non-cancerous human cells.
Pour identifier des anticorps qui se lient à des cellules cancéreuses mais non à des cellules sanguines humaines ou à des cellules normales, on utilise des cellules cancéreuses masquées au cours du processus d'immunisation. Ces anticorps conviennent à des fins thérapeutiques et/ou de diagnostic.
Bowdish Katherine S.
Dakappagari Naveen
Maruyama Toshiaki
Xin Hong
Alexion Pharmaceuticals Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Bowdish Katherine S.
Dakappagari Naveen
Maruyama Toshiaki
LandOfFree
Antibodies against cancer produced using masked cancer cells... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies against cancer produced using masked cancer cells..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies against cancer produced using masked cancer cells... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1373528