Antibodies against cd38 for treatment of multiple myeloma

Details Antibodies against cd38 for treatment of multiple myeloma Antibodies against cd38 for treatment of multiple myeloma

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 16/42 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2602375

Isolated human monoclonal antibodies which bind to human CD38, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.

La présente invention se rapporte à des anticorps monoclonaux humains, isolés, qui se lient au CD38 humain ainsi qu'à des molécules et compositions associées basées sur ces anticorps. L'invention se rapporte également à des compositions pharmaceutiques comprenant ces anticorps humains, ainsi qu'à des procédés thérapeutiques et diagnostiques d'utilisation de ces anticorps humains.

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