Antibodies against highly conserved amino acid sequences of...

Details Antibodies against highly conserved amino acid sequences of... Antibodies against highly conserved amino acid sequences of...

C - Chemistry, Metallurgy

12

P

167/139, 167/37,

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/26 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2025942

- 1 - HOE 89/F 317K Abstract of the disclosure: Antibodies against highly conserved amino acid sequences of immunogenic substances, a process for the preparation of these antibodies and the use thereof in immunoassays. The invention relates to antibodies which are obtained by immunization with a peptide fragment which represents a highly conserved amino acid sequence of a native protein. The antibodies according to the invention can be used for the preparation of immunoassays, in particular for the preparation of assays for the determination of genetic- ally engineered products such as insulin which arise as sparingly soluble inclusion bodies in microorganisms. The invention particularly relates to a multispecies insulin assay in the form of an RIA.

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