Antibodies against interleukin-10-like cytokines and uses...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/54 (2006.01) A61K 39/395 (2006.01) A61P 29/00 (2006.01) A61P 37/02 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2718634

Specific binding fragments, antibodies, and antigen-binding fragments thereof that bind IL-10-like cytokines, including human interleukin-22 (IL-22) are provided. Methods of making and using such binding fragments, antibodies, and antigen-binding fragments are also provided. Kits containing such binding fragments, antibodies, and antigen-binding fragments are also provided.

Cette invention concerne des fragments se liant de manière spécifique, des anticorps, et fragments de ceux-ci se liant à l'antigène qui se lient à des cytokines du type IL-10, comprenant l'interleukine-22 (IL-22) humaine. Des procédés pour préparer et utiliser ces fragments de liaison, anticorps, et fragments se liant à l'antigène sont également décrits. Des trousses contenant ces fragments de liaison, anticorps, et fragments se liant à l'antigène sont également décrites.

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