Antibodies against interleukin-22 and uses therefor

Details Antibodies against interleukin-22 and uses therefor Antibodies against interleukin-22 and uses therefor

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) C07K 14/54 (2006.01)

Patent

CA 2530386

Antibodies and antigen-binding fragments thereof that bind interleukin-22 (IL~ 22), in particular, human IL-22, and their uses in regulating IL-22-associated immune responses are disclosed. The antibodies disclosed herein are useful in diagnosing, preventing, or treating IL-22-associated immune disorders, e.g., autoimmune disorders (e.g., arthritis).

L'invention concerne des anticorps et des fragments de liaison à l'antigène desdits anticorps, liés à l'interleukine-22 (IL- 22), en particulier l'IL-22 humaine, et leur utilisations dans la régulation des réponses immunes associées à l'IL-22. Lesdits anticorps sont utilisés dans le diagnostic, la prévention ou le traitement des troubles immuns associés à l'IL-22, par exemple des troubles auto-immuns (par exemple l'arthrite).

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