Antibodies against phosphomannan that are protective against...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/00 (2006.01) A61K 39/395 (2006.01) C07K 16/14 (2006.01)

Patent

CA 2362840

Antibodies are disclosed that protect against candidiasis, particularly antibodies of the IgG class and antibodies that specifically bind to a carbohydrate antigen of the cell wall of a yeast from the Candida genus. Also disclosed are pharmaceutical compositions and therapeutic methods useful in the treatment of candidiasis as well as diagnostic methods.

L'invention concerne des anticorps qui protègent contre les candidoses, notamment des anticorps de la classe des IgG qui se fixent spécifiquement sur un antigène glucidique de la paroi cellulaire d'une levure du genre Candida; des compositions pharmaceutiques et des méthodes thérapeutiques utiles dans le traitement des candidoses; et des techniques diagnostiques.

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