Antibodies against phosphorylated vasp...

Details Antibodies against phosphorylated vasp... Antibodies against phosphorylated vasp...

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/395 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2308604

The invention relates to antibodies against VASP (vasodilator-stimulated phosphoprotein) which only bind VASP as an antigen when VASP is present in phosphorylated form, to hybridoma cells for their preparation, and to the use of the antibodies or antibody fragments as diagnostic agents and/or therapeutic agents.

La présente invention concerne des anticorps contre une phosphoprotéine stimulée par un vasodilatateur (VASP) qui se lient uniquement avec VASP en tant qu'antigène, lorsque VASP est présent sous forme phosphorylée. La présente invention concerne également des cellules d'hybridome utilisées pour la préparation de ces anticorps, l'utilisation de ces anticorps ou de fragments d'anticorps comme agents de diagnostic et/ou thérapeutiques.

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