Antibodies against sonic hedgehog homolog and uses thereof

Details Antibodies against sonic hedgehog homolog and uses thereof Antibodies against sonic hedgehog homolog and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01)

Patent

CA 2734330

The invention relates to targeted binding agents against human sonic hedgehog homolog (Shh) and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to Shh. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of Shh and as diagnostics.

La présente invention concerne des agents de liaison ciblés contre lhomologue du morphogène Sonic Hedgehog (Shh) humain et les utilisations de tels agents. Plus particulièrement, linvention concerne des anticorps monoclonaux entièrement humains dirigés contre le Shh. Les agents de liaison ciblés décrits sont utiles dans le traitement de maladies associées à lactivité et/ou à la surproduction de Shh et en tant que diagnostics.

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