Antibodies and a method for producing same, the use thereof...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/00 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2392423

The present invention relates to a method for producing protein-specific antibodies and to protein-specific antibodies that can be obtained therewith, i.e. polyclonal, cross-reactive antiserums having a specificity for haptoglobin of at least two working and domestic animal species. The invention also relates to the use thereof for detecting haptoglobin in samples of working and domestic animals. The invention further relates to corresponding immunisation cocktails, peptides which are useful for producing antiserums and immunoassay sets which are based upon the antiserums. Protein and protein fragments are used for immunisation.

La présente invention concerne un procédé de production d'anticorps spécifiques de protéine, les anticorps spécifiques de protéine obtenus selon ce procédé, plus précisément des antisérums à réactivité croisée, polyclonaux, à spécificité pour l'haptoglobine, issus d'au moins deux espèces d'animal d'élevage et d'animal domestique, ainsi que leur utilisation pour le dosage d'haptoglobine dans des échantillons d'animaux d'élevage et d'animaux domestiques. La présente invention concerne également des cocktails immunologiques et des peptides correspondants, qui sont utiles à la production des antisérums, ainsi que des ensembles de dosage immunologique, qui se basent sur les antisérums. Aussi bien des protéines que des fragments de protéine sont utilisés pour l'immunisation.

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