C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01)
Patent
CA 2595169
Variant antibodies and Fc fusion proteins with reduced immunogenicity are described. In particular, the variants of antibodies and Fc fusion proteins have reduced ability to bind one or more human class Il MHC molecules are described.
L'invention porte sur des variantes d'anticorps et des protéines de fusion Fc à immunogénicité réduite et en particulier sur de telles variantes présentant une capacité réduite de fixation à une ou plusieurs molécules MHC humaines de classe II.
Marshall Shannon Alicia
Moore Gregory L.
Marshall Shannon Alicia
Moore Gregory L.
Smart & Biggar
Xencor Inc.
LandOfFree
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