C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/20 (2006.01) C07K 14/445 (2006.01) C12N 5/20 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2372213
Novel peptides comprising an amino acid sequence which is repeated in the <i>P. vivax</i> ESP-1 protein (PvESP-1) are disclosed. Also disclosed are antibodies generated in response to immunization with these peptides which exhibit high specificity and sensitivity for <i>P. vivax</i> antigens in diagnostic assays. Assay methods employing the inventive antibodies and kits for carrying out the inventive methods are also provided.
L'invention concerne de nouveaux peptides comprenant une séquence d'acides aminés répétée dans la protéine ESP-1 <i>P. vivax</i> (PvESP-1). L'invention concerne également des anticorps générés en réponse à l'immunisation avec ces peptides, présentant une grande spécificité et sensibilité aux antigènes <i>P. vivax</i> dans des méthodes diagnostiques. L'invention concerne également des méthodes d'analyse dans lesquelles sont utilisés lesdits anticorps et des kits pour mettre en oeuvre ces méthodes.
Baggett David W.
Carrigan Michelle C.
Mallonee Richard L.
Maret S. Melissa
Becton Dickinson And Company
Gowling Lafleur Henderson Llp
LandOfFree
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