Antibodies and pharmaceutical compositions containing same...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 233/61 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2678304

The present invention relates to a compound having the general Formula: (I); wherein: m and n are each independently an integer from 1 to 6; X1-X3 and Y1 -Y3 are each independently O or S; R1-R3 are each independently selected from the group consisting of hydrogen, alkyl, and cycloalkyl; and i R is (CH2)x-C(-O)NR'-(CH2)y-NR'R" whereas: x and y are each independently an integer from 1 to 6; and R' and R" arc each independently selected from the group consisting of, hydrogen, alkyl, and cycloalkyl; and to an antibody comprising an antigen recognition region capable of specifically binding the above compound.

La présente invention concerne un composé représenté par la formule (I) dans laquelle m et n représentent chacun indépendamment un entier compris entre 1 et 6; X1-X3 et Y1 -Y3 représentent chacun indépendamment O ou S; R1-R3 sont chacun indépendamment sélectionnés dans le groupe formé par: hydrogène, alkyle et cycloalkyle; et i R représente (CH2)x-C(-O)NR'-(CH2)y-NR'R" alors que x et y représentent chacun indépendamment un entier compris entre 1 et 6; et R' et R" sont chacun indépendamment sélectionnés dans le groupe formé par: hydrogène, alkyle et cycloalkyle. Cette invention porte également sur un anticorps comprenant une région de reconnaissance d'antigène capable de se lier spécifiquement au composé de l'invention.

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