Antibodies binding to a c-terminal fragment of apolipoprotein e

Details Antibodies binding to a c-terminal fragment of apolipoprotein e Antibodies binding to a c-terminal fragment of apolipoprotein e

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 25/00 (2006.01) C12N 15/13 (2006.01) G01N 33/53 (2006.01) C07K 14/775 (2006.01)

Patent

CA 2547675

A human antibody fragment, which antibody or fragment: (i) binds to a polypeptide having the amino acid sequence shown in SEQ ID NO: 1 of the C- terminal domain of Apolipoprotein E (ApoE-CTD) or the amino acid sequence of a part thereof; and (ii) binds to human plaques.

L'invention concerne un fragment d'anticorps humain. Ledit anticorps ou fragment d'anticorps : (i) se fixe sur un polypeptide comportant la séquence d'acides aminés SEQ ID NO: 1 du domaine C-terminal de l'Apolipoprotéine E (ApoE-CTD) ou la séquence d'acides aminés d'une partie de ce domaine ; (ii) se fixe sur les plaques humaines.

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