Antibodies binding to human trypsin-like protease and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/06 (2006.01) A61K 39/395 (2006.01) A61P 11/00 (2006.01) A61P 11/04 (2006.01) A61P 11/06 (2006.01) A61P 11/10 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12Q 1/37 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2362649

A method of diagnosing pathogenic conditions based on the assay of human airway trypsin-like enzyme in biological samples and remedies for diseases in which human airway trypsin-like enzyme participates. An antibody binding to human airway trypsin-like enzyme; an enzyme immunoassay method with the use of the same; remedies containing an antibody inhibiting the activation of human airway trypsin-like enzyme; and remedies containing an antibody neutralizing the activity of human airway trypsin-like enzyme.

L'invention concerne un procédé de diagnostic d'états pathogènes, basé sur le dosage de l'enzyme du type trypsine des voies aériennes humaines dans des échantillons biologiques, et des remèdes contre des maladies auxquelles participe l'enzyme du type trypsine des voies aériennes humaines. L'invention se rapporte à un anticorps se liant à l'enzyme du type trypsine des voies aériennes humaines ; à des remèdes contenant un anticorps inhibant l'activation de l'enzyme du type trypsine des voies aériennes humaines ; et à des remèdes contenant un anticorps neutralisant l'activité de l'enzyme du type trypsine des voies aériennes humaines.

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