Antibodies binding to the extracellular domain of the...

Details Antibodies binding to the extracellular domain of the... Antibodies binding to the extracellular domain of the...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/00 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2650822

The present invention concerns an antibody specific for human ALK (Anaplastic Lymphoma Kinase), in particular a scFv, a nucleic acid sequence encoding it, its production and its use as a pharmaceutical or for diagnostic purposes. Said antibody is suitable for the local treatment of tumors, in particular glioblastoma.

La présente invention concerne un anticorps spécifique de l'ALK humaine (Kinase de lymphome anaplasique), en particulier un anticorps scFv, une séquence d'acides nucléiques codant cet anticorps, ainsi que la production et l'utilisation de cet anticorps comme agent pharmaceutique ou à des fins diagnostiques. L'anticorps de cette invention peut être utilisé pour le traitement local de tumeurs, en particulier du glioblastome.

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