Antibodies directed against amyloid-beta peptide and methods...

Details Antibodies directed against amyloid-beta peptide and methods... Antibodies directed against amyloid-beta peptide and methods...

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2575663

Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and A.beta. peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and A.beta. peptide associated diseases are also described.

L'invention porte sur l'anticorps monoclonal 9TL et sur des anticorps en dérivant dirigés contre le peptide amyloïde bêta et sur leurs procédés d'utilisation pour diagnostiquer et traiter la maladie d'Alzheimer et les maladies associées au peptide Aß. L'invention porte également sur des procédés d'utilisation d'anticorps dirigés contre le peptide amyloïde bêta, a fonction effecteur affaiblie, pour traiter la maladie d'Alzheimer et les maladies associées au peptide Aß.

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