Antibodies directed to angiopoietin-1 and angiopoietin-2 and...

Details Antibodies directed to angiopoietin-1 and angiopoietin-2 and... Antibodies directed to angiopoietin-1 and angiopoietin-2 and...

C - Chemistry, Metallurgy

07

K

C07K 16/22 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/00 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2715324

Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin 1 and/or angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.

La présente invention concerne des agents de liaison spécifiques, tels que des anticorps pleinement humains, qui se lient à l'angiopoïétine 1 et/ou à l'angiopoïétine 2. L'invention concerne également des fragments de chaînes lourdes, des fragments de chaînes légères et des régions déterminant la complémentarité (CDR) des anticorps, ainsi que des procédés de fabrication et d'utilisation desdits anticorps.

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