Antibodies directed to angiopoietin-2 and uses thereof

Details Antibodies directed to angiopoietin-2 and uses thereof Antibodies directed to angiopoietin-2 and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2595610

Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementary determining regions (CDR~s), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobin molecules and monoclonal antibodies.

La présente invention a trait à des anticorps dirigés contre l'angiopoïétine 2 et à des utilisations de tels anticorps, notamment, des anticorps monoclonaux entièrement humains dirigés contre l'antigène angiopoïétine 2, à des séquences nucléotidiques codant pour, et à des séquences d'acides aminés comportant, des molécules d'immunoglobuline à chaînes lourdes et légères, en particulier des séquences correspondant aux séquences à chaînes lourdes et chaînes légères contiguës recouvrant des régions charpente et/ou des régions déterminant de la complémentarité, spécifiquement depuis la région charpente 1 jusqu'à la région charpente 4 ou depuis la région 1 déterminant de la complémentarité jusqu'à la région 3 déterminant de la complémentarité, à des hybridomes ou autres lignées cellulaires d'expression de telles molécules d'immunoglobuline et de tels anticorps monoclonaux.

Affiliated with

Also associated with

Rating

Antibodies directed to angiopoietin-2 and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies directed to angiopoietin-2 and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies directed to angiopoietin-2 and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1956493