Antibodies directed to dll4 and uses thereof

Details Antibodies directed to dll4 and uses thereof Antibodies directed to dll4 and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/22 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2735900

The invention relates to targeted binding agents against DLL4 and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to DLL4. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of DLL4 and as diagnostics.

L'invention concerne des agents de liaison ciblés contre DLL4 et l'utilisation de tels agents. De manière plus spécifique, l'invention concerne des anticorps monoclonaux totalement humains dirigés contre DLL4. Les agents de liaison ciblés décrits sont utiles dans le traitement de maladies associées à l'activité et/ou la surproduction de DLL4 et en tant qu'agents de diagnostic.

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