C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2361877
The present application describes a method for making antibodies which can be used for cancer diagnosis or therapy. The application also discloses a method for identifying an antigen which is differentially expressed on the surface of two or more distinct cell populations. The application additionally describes human antibodies directed against decay accelerating factor (DAF), as well as therapeutic compositions comprising such antibodies. Moreover, the application disclosed a method of treating lung cancer with antibodies directed against DAF.
La présente invention concerne une méthode de production d'anticorps pouvant s'utiliser pour établir un diagnostic du cancer ou pour traiter un cancer. L'invention concerne également une méthode permettant de déterminer un antigène à expression différentielle à la surface de deux ou plusieurs populations cellulaires distinctes. L'invention concerne en outre des anticorps humains anti-facteur accélérateur de dissociation, ainsi que des compositions thérapeutiques contenant ces anticorps. L'invention concerne enfin une méthode de traitement du cancer du poumon avec des anticorps anti-facteur accélérateur de dissociation.
Carter Paul J.
Ridgway John B.
Genentech Inc.
Smart & Biggar
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