Antibodies for the detection of hla-g

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) C07K 14/74 (2006.01) C07K 16/28 (2006.01) C12N 5/18 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2213620

The Class I molecule HLA-G is specifically expressed by invasive cytotrophoblasts. Antigens which elicit antibodies specific for HLA-G, and antibodies which bind these antigens are provided. Methods related to the measurement of HLA-G levels in biological fluids are also provided.

La molécule HLA-G de classe I est spécifiquement exprimée par des cytotrophoblastes invasifs. L'invention décrit des antigènes qui élicitent des anticorps spécifiques de HLA-G et des anticorps qui fixent ces antigènes. L'invention décrit également des procédés liés à la mesure des taux de HLA-G dans les liquides biologiques.

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