Antibodies specific for cancer associated antigen sm5-1 and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/30 (2006.01) C12N 5/22 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) G01N 33/53 (2006.01) G01N 33/563 (2006.01)

Patent

CA 2528182

The invention concerns antibodies which is specific for SM5-1 antigen expressed in melanoma, breast cancer and hepatocellular carcinoma, and polynucleotides encoding the antibodies. The invention further concerns use of such antibodies and/or polynucleotides in diagnosing and treating malignancies.

L'invention concerne des anticorps qui sont spécifiques de l'antigène SM5-1 exprimé dans les mélanomes, le cancer du sein et les carcinomes hépatocellulaires ; ainsi que des polynucléotides codant ces anticorps. L'invention concerne en outre l'utilisation desdits anticorps et/ou polynucléotides dans le diagnostic et le traitement de tumeurs malignes.

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