C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01)
Patent
CA 2646478
The present invention relates to blocking, inhibiting, reduceing, antagonizing or neutralizing the activity of IL-17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. The present invention includes antibodies that bind both IL-17A and IL-17F, as well as methods of using the same in inflammation.
Blocage, inhibition, réduction, antagonisation ou neutralisation de l'activité d'IL-17A et IL-17F. IL-17A et IL-17F sont des cytokines intervenant dans les processus inflammatoires et les maladies humaines. On décrit des anticorps se liant à la fois avec IL-17A et IL-17F et des procédés d'utilisation correspondants contre l'inflammation.
Jaspers Stephen R.
Levin Steven D.
Presnell Scott R.
Rixon Mark W.
Osler Hoskin & Harcourt Llp
Zymogenetics Inc.
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