Antibodies that bind both il-17a and il-17f and methods of...

Details Antibodies that bind both il-17a and il-17f and methods of... Antibodies that bind both il-17a and il-17f and methods of...

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) C12N 5/18 (2006.01)

Patent

CA 2682889

The present invention relates to blocking, inhibiting, reduceing, antagonizing or neutralizing the activity of IL-17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. The present invention includes antibodies that bind both IL-17A and IL-17F, hybridomas that produce the antibodies, an methods of using the same in inflammation.

La présente invention porte sur le blocage, l'inhibition, la réduction, l'antagonisation ou la neutralisation de l'activité de l'IL-17A et de l'IL-17F. IL-17A et IL-17F sont des cytokines qui sont mises en jeu dans des processus inflammatoires et une maladie humaine. La présente invention comprend des anticorps qui lient à la fois IL-17A et IL-17F, des hybridomes qui produisent les anticorps ainsi que des procédés pour leur utilisation dans l'inflammation.

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