Antibodies that bind il-4 and/or il-13 and their uses

Details Antibodies that bind il-4 and/or il-13 and their uses Antibodies that bind il-4 and/or il-13 and their uses

C - Chemistry, Metallurgy

07

K

C07K 16/46 (2006.01) A61K 39/395 (2006.01) A61P 11/06 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2702473

The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.

La présente invention concerne de nouveaux anticorps anti-IL-4 et IL-13 humanisés et des fragments de ceux-ci et de nouveaux anticorps bispécifiques et des fragments de ceux-ci qui se lient spécifiquement au IL-4 et IL-13. L'invention concerne également des utilisations des anticorps pour traiter ou prévenir des maladies ou troubles induits par l'IL-4 et/ou l'IL-13, y compris l'asthme allergique et la dermatose.

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