Antibodies that bind interleukin-4 receptor

Details Antibodies that bind interleukin-4 receptor Antibodies that bind interleukin-4 receptor

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2543982

The present invention relates to antibodies that bind to the IL-4 receptor, fragments, muteins, and derivatives of such antibodies, nucleic acids encoding such antibodies, fragments, muteins and derivatives, and methods of making and using such antibodies, fragments, muteins, derivatives and nucleic acids. Methods for treating medical conditions induced by interleukin-4 involve administering an IL-4 receptor binding antibody, or an IL-4 receptor binding fragment, mutein, or derivative of an IL-4 receptor binding antibody, to a patient afflicted with such a condition. Particular antibodies provided herein include human monoclonal antibodies. Certain of the antibodies inhibit both IL- 4-induced and IL-13-induced biological activities.

L'invention concerne des anticorps qui lient le récepteur de IL-4, des fragments, des mutéines, et des dérivés desdits anticorps, des acides nucléiques codant lesdits anticorps, des fragments, des mutéines et des dérivés, et des procédés pour fabriquer lesdits anticorps, leurs fragments, leurs mutéines, leurs dérivés et leurs acides nucléiques. L'invention concerne des méthodes de traitement d'états pathologiques induits par l'interleucine 4 comprenant l'administration d'un anticorps de liaison du récepteur d'IL-4, ou un fragment de liaison du récepteur d'IL-4, une mutéine, ou un dérivé d'un anticorps de liaison du récepteur d'IL-4, à un patient souffrant dudit état pathologique. Des anticorps particuliers comprennent des anticorps humains. Certains anticorps inhibent à la fois les activités biologiques induites par l'IL-4 et l'IL-13.

Affiliated with

Also associated with

Rating

Antibodies that bind interleukin-4 receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies that bind interleukin-4 receptor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies that bind interleukin-4 receptor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1398083