Antibodies that bind to epha2 and methods of use thereof

Details Antibodies that bind to epha2 and methods of use thereof Antibodies that bind to epha2 and methods of use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2597198

Provided herein is disclosure about the development and characterization of an antibody that binds to antigen EphA2 which is present on a variety of human cancers from breast, lung, prostate, and colons. Methods of diagnosing and treating various cancers by using such antibodies directed against this antigen are also disclosed.

L'invention concerne la mise au point et la caractérisation d'un anticorps qui se lie à l'antigène EphA2, lequel antigène est présent dans divers cancers humains tels que le cancer du sein, du poumon, de la prostate et du côlon. Par ailleurs, l'invention concerne des méthodes de diagnostic et de traitement de divers types de cancers au moyen de ces anticorps dirigés contre l'antigène dont il est question.

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