Antibodies that immunospecifically bind to trail receptors

Details Antibodies that immunospecifically bind to trail receptors Antibodies that immunospecifically bind to trail receptors

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C07K 17/00 (2006.01) C12N 5/10 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2446723

The present invention relates to antibodies and related molecules that immunospecifically bind to TRAIL receptor, TR4. Such antibodies have uses, for example, in the prevention and treatment of cancers and other proliferative disorders. The invention also relates to nucleic acid molecules encoding anti- TR4 antibodies, vectors, and host cells containing these nucleic acids, and methods for producing the same. The present invention relates to methods and compositions for preventing, detecting, diagnosing, treating, or ameliorating a disease or disorder, especially cancer and other hyperproliferative disorders, comprising administering to an animal, preferably a human, an effective amount of one or more antibodies or fragments or variants thereof, or related molecules, that immunospecifically bind to TRAIL receptor TR4.

La présente invention se rapporte à des anticorps et à des molécules associées qui se lient de manière immunospécifique au récepteur de TRAIL, TR4. Ces anticorps s'avèrent utiles, par exemple, pour prévenir et traiter des cancers et d'autres troubles prolifératifs. Cette invention se rapporte à des molécules d'acides nucléiques codant des anticorps anti-TR4, à des vecteurs et à des cellules hôtes contenant ces acides nucléiques ainsi qu'à des procédés de production de ces derniers. La présente invention se rapporte à des procédés et à des compositions permettant de prévenir, détecter, diagnostiquer, traiter ou améliorer un état pathologique ou un trouble, en particulier un cancer ou tout autre trouble hyperprolifératif, lesdits procédés consistant à administrer à un animal, de préférence un humain, une quantité efficace d'un ou de plusieurs des anticorps ou fragments ou variants de ces anticorps, ou des molécules associées, qui se lient de manière immunospécifique au récepteur TR4 de TRAIL.

Affiliated with

Also associated with

Rating

Antibodies that immunospecifically bind to trail receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies that immunospecifically bind to trail receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies that immunospecifically bind to trail receptors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1834163