Antibodies that recognize app cleaved by caspases and...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 16/18 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) C07K 16/28 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2363984

Amyloid-.beta. peptide (A.beta.) formation and the apoptotic loss of neurons are intimately linked processes in the pathogenesis of neurodegenerative diseases, particularly Alzheimer's disease. The roles of apoptotic proteases and caspases in cleavage of amyloid-.beta. precursor protein (APP) and biogenesis of amyloidogenic A.beta. peptide species are described. Antibodies that recognize caspase cleaved APP are described as well as various utilities therefore.

La formation du peptide .beta.-amyloïde (A.beta.) et la perte de neurones par apoptose sont des processus intimement liés dans la pathogénèse des maladies neurodégénératives, et notamment la maladie d'Alzheimer. L'invention concerne les rôles des protéases et caspases apoptotiques dans le clivage de la protéine précurseur amyloïde-.beta. (APP) et dans la biogénèse des espèces peptidiques amyloïdogènes A.beta.. L'invention concerne également des anticorps reconnaissant l'APP clivée par une caspase, ainsi que leurs nombreuses utilisations.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Antibodies that recognize app cleaved by caspases and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies that recognize app cleaved by caspases and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies that recognize app cleaved by caspases and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1856722

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.